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MATERIALS AND METHODS RBCs preparation and sampling This study was a simple random study, in which the packed LR-RBCs (n = 10) were collected from the healthy donor volunteers following the guidelines of the Iranian Blood Transfusion Organization (IBTO)

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We observed that predicting aqueous solubility was consistently superior to predicting intrinsic solubilityaqueous-solubility-prediction models generally had an of 0.750.80 while intrinsic-solubility-prediction models had an of 0.550.65 (Figure 2)